Description

DexaPico is a cough syrup for children. It contains the antitussive dextromethorphan hydrobromide and irritation-soothing linden flower extract.

Composition

The active substances are: aqueous extract of linden inflorescence ( Tiliae inflorescentiae extractum aquosum ) and dextromethorphan hydrobromide ( Dextromethorphani hydrobromidum ).

100 g of syrup contains: aqueous extract of linden inflorescence (1:5) 25 g and dextromethorphan hydrobromide 0.1 g.

Excipients: sucrose, concentrated chokeberry juice 65%, citric acid monohydrate, sodium benzoate, potassium sorbate, raspberry flavor 7111, purified water.

Dosage

DexaPico is administered orally.
In the case of children aged 2-12 years, the drug is administered only on the express recommendation of a doctor.

The usual recommended dose is:

• for children aged 2 - 6 years: 2.5 ml of syrup 3 times a day,
• for children aged 6-12: 5 ml of syrup 3 times a day,
• adolescents over 12 years of age and adults: 15 ml of syrup 3 times a day.

Do not exceed the recommended dosage.

If symptoms persist for more than 7 days, you have a recurring cough, or a cough accompanied by fever, rash, or persistent headache, consult your doctor or pharmacist. These may be signs of a serious condition.

Action

DexaPico contains dextromethorphan hydrobromide and linden flower extract.

Dextromethorphan hydrobromide has an antitussive effect, reducing the frequency of dry cough by inhibiting the cough center in the central nervous system. Its effect lasts for 6 to 8 hours.

Linden flower extract soothes irritation of the upper respiratory tract caused by cough.

Indications

Dexapico is used in cases of tiring, dry cough of various origins, but not related to the retention of secretions in the respiratory tract.

Contraindications

When not to use DexaPico :

• if you are allergic to any of the ingredients of the medicine
• in case of cough with a large amount of sputum,
• if you suffer from bronchial asthma,
• in patients with severe respiratory failure or at risk of its development,
• in case of severe liver disease,
• while taking monoamine oxidase inhibitors (MAO) and within 14 days of discontinuing them,
• if you are taking selective serotonin reuptake inhibitors (SSRIs),
• when using mucolytic drugs (thinning mucus in the respiratory tract).

Side effects

Like all medicines, DexaPico can cause side effects, although not everybody gets them.

Rare side effects (affecting less than 1 in 1,000 people):

• somnolence

Frequency unknown:

• agitation, confusion;
• dizziness, convulsions;
• respiratory depression; vomiting, nausea, diarrhea,
• rash.

Warnings and precautions

Do not use in children under 2 years of age.

This product contains sucrose (3.9 g in 5 ml of syrup), which should be taken into account by patients with diabetes. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.

If you have a chronic or persistent cough, consult your doctor before using this medicine.

Caution should be exercised in patients with hepatic impairment.

Caution should be exercised in patients who are poor CYP2D6 metabolisers or who are concomitantly taking CYP2D6 inhibitors.

Drinking alcohol is not recommended during treatment.

• Store the medicine at a temperature below 25°C in a tightly closed container.
• Keep the medicine out of the sight and reach of children.

Use of other medications

Tell your doctor about all the medicines you are taking, have recently taken or are planning to take.

• MAO inhibitors: DexaPini should not be used in patients who are taking them or within 14 days of stopping treatment, as it may lead to serotonin syndrome;
• Linezoid: when used concomitantly with dextromethorphan hydrobromide, serotonin syndrome may occur;
• CYP2D6 inhibitors: Concomitant use of strong CYP2D6 inhibitors may increase dextromethorphan concentrations to levels many times higher than normal. Strong CYP2D6 inhibitors include fluoxetine, paroxetine, quinidine, and terbinafine. Amiodarone, flecainide and propafenone, sertraline, bupropion, methadone, cinacalcet, haloperidol, perphenazine, and thioridazine also have a similar effect on dextromethorphan metabolism.
• Other central nervous system depressants and alcohol may enhance the depressant effect of dextromethorphan hydrobromide on the central nervous system and be toxic at relatively low doses.

Pregnancy and breastfeeding

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Do not use in pregnant or breastfeeding women.

Use of the drug in children and adolescents

Do not use in children under 2 years of age.

Driving and operating machinery

Due to the possibility of drowsiness, caution should be exercised when driving or operating machinery.